Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates

Caenorhabditis elegans is one of the principle models used to study aging because of its excellent genetics and short lifespan of three weeks. More recently, C.elegans has emerged as a model organism for phenotype based drug screens because of its small size and its ability to grow in microtiter plates.

This publication and video  presented an assay to measure C.elegans lifespan in 96 well microtiter plates. The assay was developed and successfully used to screen large libraries for molecules that extend C.elegans lifespan.