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PhD position: Genomics basis of the arms race between a parasite and its host, the threespine stickleback

17 Mai 2017,

Publié par Bioécologie

A fully-funded 4-year PhD position is available in the Aubin-Horth and Landry Laboratories at Universite Laval in Quebec City, Canada. The PhD student will work on a project aimed at dissecting the genomic bases of the co-evolution between the threespine stickleback and its worm parasite, Schistocephalus solidus.

The candidate is expected to have a Master degree in biology or a related discipline, and a background in bioinformatics (R, Python or Perl), statistics and genomics. The candidate should have strong leadership skills, motivation and creativity and be able to work in a team of collaborators.

The Aubin-Horth and Landry Laboratories are located at the Institut de Biologie Intégrative et des Systèmes (IBIS) at Université Laval. IBIS offers a very stimulating training environment and cutting edge on-site platforms in genomics, proteomics and microscopy. The Aubin-Horth Lab members are evolutionary biologists, neuroendocrinologists and behaviour biologists working together using an integrative approach to uncover the mechanisms underlying the alteration of stickleback behaviour by its endoparasite, by studying both the host and its parasite at the molecular, cellular and hormonal level, as well as how they interact. The Landry lab is an international team of 15 students, PDFs and research associates from different backgrounds (microbiology, biology, bioinformatics, biochemistry) addressing questions in evolutionary cell and systems biology.

The application package (1 single PDF file) should include a motivation letter demonstrating the interest of the candidate for the field and his/her ability to perform this type of research, a CV and the contact information of three people who can provide letters of reference. The file should be sent to Nadia.Aubin-Horth@bio.ulaval.ca

Starting date could be as early as September 2017. The competition will remain open until a candidate is selected.

-For more information on research ongoing in the Aubin-Horth and Landry laboratories, please visit:
http://wikiaubinhorth.ibis.ulaval.ca/Main_Page
http://landrylab.ibis.ulaval.ca/

-Recent publications from the two laboratories on this subject:

Hébert FO, Grambauer S, Barber I, Landry CR, Aubin-Horth N. Major host
transitions are modulated through transcriptome-wide reprogramming events in
Schistocephalus solidus, a threespine stickleback parasite. 2-17. Molecular Ecology. 26:1118-1130.

Grécias L, Hébert FO, Berger CS, Barber I, Aubin-Horth N. 2017. Can the behaviour of
threespine stickleback parasitized with Schistocephalus solidus be replicated by
manipulating host physiology? J Experimental Biology. 15: 237-246. doi:
10.1242/jeb.151456. Epub 2016 Nov 3. PubMed PMID: 27811294.

Hébert FO, Grambauer S, Barber I, Landry CR, Aubin-Horth N. 2016. Transcriptome
sequences spanning key developmental states as a resource for the study of the
cestode Schistocephalus solidus, a threespine stickleback parasite. Gigascience. 5:24.

Hebert FO, Phelps L, Samonte I, Panchal M, Grambauer S, Barber I, Kalbe M,
Landry CR, Aubin-Horth N. 2015. Identification of candidate mimicry proteins involved
in parasite-driven phenotypic changes. Parasites and Vectors. 15 :225.

Hébert FO, Aubin-Horth N. 2014. Ecological genomics of host behavior manipulation by parasites.
Adv Exp Med Biol. 781:169-90. d

Landry CR, Aubin-Horth N. 2014. Recent advances in ecological genomics: from
phenotypic plasticity to convergent and adaptive evolution and speciation. Adv
Exp Med Biol. 781:1-5.

Pavey SA, Bernatchez L, Aubin-Horth N, Landry CR. 2012. What is needed for
next-generation ecological and evolutionary genomics? Trends in Ecology and Evolution. 27:673-8.

________________________________
Christian Landry, PhD
Professeur agrégé

Chaire de Recherche du Canada en Biologie évolutive des systèmes cellulaires
// Canada Research Chair in Evolutionary Cell and Systems Biology

Département de Biologie
Institut de Biologie Intégrative et des Systèmes
PROTEO
Centre de recherche en données massives (CRDM)

Local 3106, Pavillon Charles-Eugène-Marchand
1030, Avenue de la Médecine
Université Laval
Québec (Québec) G1V 0A6
Canada

http://landrylab.ibis.ulaval.ca/
http://journalclub.ibis.ulaval.ca/

AnaEE-France (Analyses et Expérimentations sur les Ecosystèmes - France)

6 Mai 2017,

Publié par Bioécologie

AnaEE-France est une infrastructure nationale de recherche dédiée à l’étude des écosystèmes continentaux et de leur biodiversité.

Elle met à la disposition de la communauté scientifique internationale 22 services composés de plateformes expérimentales (en milieu contrôlé, semi-naturel ou naturel), de plateformes d’analyses et d’instrumentation partagée.

AnaEE France permet aussi un accès aux données et à des plateformes de modélisation.

 

Les activités humaines ont considérablement altéré les milieux naturels à travers le monde et soulèvent des questions sociétales vitales telles que la fourniture pérenne de ressources biologiques et de services écologiques. Dans ce contexte, un défi scientifique majeur consiste à comprendre et prédire la dynamique de la biodiversité et des écosystèmes. Pour cela, nous avons besoin d’une véritable biologie intégrée combinant les sciences du vivant et environnementales. L’infrastructure AnaEE France « Analyse et Expérimentation sur les Ecosystèmes - France » répond à cet enjeu. Elle est coordonnée par le CNRS, l’INRA et l’Université Joseph Fourier, et constitue la contribution française au projet européen AnaEE inscrit sur la feuille de route du Forum européen sur les infrastructures de recherche (ESFRI).

Vuelo nocturno – The magic of flying at night

29 Avril 2017,

Publié par Bioécologie

An amazing video, filmed from the flight deck of a commercial long-haul flight, has captured a view of the night sky not usually seen by slumbering passengers. The video, shot by pilot Sales Wick.

Une magnifique vidéo réalisée par le pilote Sales Wick au cours d'un vol commercial. 

La plateforme GenoSol

6 Avril 2017,

Publié par Bioécologie

La plateforme GenoSol de l’UMR Agroécologie de l’INRA de Dijon est une structure unique en Europe, centrée sur la (micro)biologie des sols. Ses missions s’articulent autour de trois activités principales : un Conservatoire des Ressources Génétiques Microbiennes, une Plateforme Technique de caractérisation moléculaire du métagénome microbien, un Système d’Information sur la diversité microbienne des sols et de l’environnement. Depuis 2015, la Plateforme GenoSol est certifiée ISO 9001 pour le Conservatoire des Ressources Génétiques Microbiennes.

La plateforme GenoSol

The eDNA platform

6 Avril 2017,

Publié par Bioécologie

This technical platform has been set up to allow ecologists to perform large-scale analysis of environmental DNA via a metabarcoding approach. DNA metabarcoding refers to high throughput DNA-based identification of multiple species from environmental DNA. The main applications consist in diet analysis from feces, in biodiversity assessment using soil or water samples, and in palaeo-environment reconstruction using lake sediments and permafrost samples.

The eDNA platform is composed of three pre-PCR extraction rooms dedicated to feces, soil, and ancient DNA, and to several post-PCR rooms dedicated to the purification and the titration of PCR products. The next generation sequencing on Illumina platforms (HiSeq or MiSeq) is outsourced.

The eDNA platform