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Bioécologie

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

13 Septembre 2017,

Publié par Bioécologie

The OECD launched a new programme on the development of Adverse Outcome Pathways (AOP) in 2012. An AOP is an analytical construct that describes a sequential chain of causally linked events at different levels of biological organisation that lead to an adverse health or ecotoxicological effect (see figure below). AOPs are the central element of a toxicological knowledge framework being built to support chemical risk assessment based on mechanistic reasoning.

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

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